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Article

Late-onset Alzheimer disease risk variants mark brain regulatory loci

1 Aug 2015

Abstract excerpt

OBJECTIVE: To investigate the top late-onset Alzheimer disease (LOAD) risk loci detected or confirmed by the International Genomics of Alzheimer's Project for association with brain gene expression levels to identify variants that influence Alzheimer disease (AD) risk through gene expression regulation. METHODS: Expression levels from the cerebellum (CER) and temporal cortex (TCX) were obtained using Illumina...

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PMID: 27066552
DOI: 10.1212/nxg.0000000000000012

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