Article
Bayesian analysis of complex interacting mutations in HIV drug resistance and cross-resistance.
Advances in experimental medicine and biology - 1 Jan 2015
Kozyryev Ivan, Zhang Jing
Abstract excerpt
A successful treatment of AIDS world-wide is severely hindered by the HIV virus' drug resistance capability resulting from complicated mutation patterns of viral proteins. Such a system of mutations enables the virus to survive and reproduce despite the presence of various antiretroviral drugs by disrupting their binding capability. Although these interacting mutation patterns are extremely difficult to...
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