Article
Inherited variation at MC1R and ASIP and association with melanoma-specific survival.
International journal of cancer - 1 Jun 2015
Taylor Nicholas J, Reiner Anne S, Begg Colin B, Cust Anne E, Busam Klaus J, Anton-Culver Hoda, Dwyer Terence, From Lynn, Gallagher Richard P, Gruber Stephen B, Rosso Stefano, White Kirsten A, Zanetti Roberto, Orlow Irene, Thomas Nancy E, Rebbeck Timothy R, Berwick Marianne, Kanetsky Peter A
Abstract excerpt
Melanocortin-1 receptor (MC1R) is a marker of melanoma risk in populations of European ancestry. However, MC1R effects on survival are much less studied. We investigated associations between variation at MC1R and survival in an international, population-based series of single primary melanoma patients enrolled into the Genes, Environment, and Melanoma study. MC1R genotype data was available for 2,200 participants...
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