Article
MC1R variants and cutaneous melanoma risk according to histological type, body site, and Breslow thickness: a pooled analysis from the M-SKIP project.
Melanoma research - 1 Oct 2020
Caini Saverio, Gandini Sara, Botta Francesca, Tagliabue Elena, Raimondi Sara, Nagore Eduardo, Zanna Ines, Maisonneuve Patrick, Newton-Bishop Julia, Polsky David, Lazovich DeAnn, Kumar Rajiv, Kanetsky Peter A, Hoiom Veronica, Ghiorzo Paola, Landi Maria Teresa, Ribas Gloria, Menin Chiara, Stratigos Alexander J, Palmieri Giuseppe, Guida Gabriella, García-Borrón Jose Carlos, Nan Hongmei, Little Julian, Sera Francesco, Puig Susana, Fargnoli Maria Concetta
Abstract excerpt
Little is known on whether melanocortin 1 receptor (MC1R) associated cutaneous melanoma (CM) risk varies depending on histological subtype and body site, and whether tumour thickness at diagnosis (the most important prognostic factor for CM patients) differs between MC1R variant carriers and wild-type individuals. We studied the association between MC1R variants and CM risk by histological subtype, body site, and...
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