Melanocortin 1 receptor and risk of cutaneous melanoma: a meta-analysis and estimates of population burden.

doi:10.1002/ijc.25804

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Article

Melanocortin 1 receptor and risk of cutaneous melanoma: a meta-analysis and estimates of population burden.

International journal of cancer - 1 Oct 2011

Williams Patricia F, Olsen Catherine M, Hayward Nicholas K, Whiteman David C

Abstract excerpt

Polymorphisms in the melanocortin 1 receptor (MC1R) gene have been associated with increased risks of melanoma, but different approaches to study design, analysis, and reporting have hindered comparisons of findings. We aimed to harmonize the published data by conducting a systematic review and meta-analysis of MC1R variants and thereby estimate relative risks and population attributable fractions (PAFs). We...

Topics

Case-Control Studies
Gene Frequency
Genetic Variation
Humans
Melanoma
Middle Aged
Receptor, Melanocortin, Type 1
Risk Factors
Skin Neoplasms

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Open in PubMed

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PMID: 21128237
DOI: 10.1002/ijc.25804

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