Article
Revisiting heritability accounting for shared environmental effects and maternal inheritance.
Human genetics - 1 Feb 2015
Liu Chunyu, Dupuis Josée, Larson Martin G, Cupples L Adrienne, Ordovas Jose M, Vasan Ramachandran S, Meigs James B, Jacques Paul F, Levy Daniel
Abstract excerpt
Heritability measures the proportion of phenotypic variation attributable to genetic factors. In addition to a shared nuclear genetic component, a number of additional variance components, such as spousal correlation, sibship, household and maternal effects, may have strong contributions to inter-individual phenotype variation. In humans, the confounding effects of these components on heritability have not been...
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