Article
Constitutive activation of the renin-angiotensin system reduces visceral fat and improves glucose tolerance in mice.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2014
Favre Guillaume A, Lebrun Patricia, Lopez Pascal, Butori Catherine, Hofman Paul, Esnault Vincent Lm, Van Obberghen Emmanuel
Abstract excerpt
INTRODUCTION: The renin-angiotensin system (RAS), and particularly angiotensin II, is involved in the control of energy balance, glucose homeostasis and kidney functions. The integrated impact of the RAS on glucose homeostasis is still a matter of debate. MATERIALS AND METHODS: We used a model of constitutive RAS activation in double transgenic mice (dTGM) carrying both human angiotensinogen and human renin...
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