Article
Olig3 is not involved in the ventral patterning of spinal cord.
PloS one - 1 Jan 2014
Liu Zijing, Hu Xuemei, Huang Chengcheng, Zheng Kang, Takebayashi Hirohide, Cao Cheng, Qiu Mengsheng
Abstract excerpt
At embryonic stages, Olig3 is initially expressed in the dorsal-most region of the spinal cord, but later in the ventral marginal zone as well. Previous studies indicated that Olig3 controlled the patterning of dorsal spinal cord and loss of Olig3 function led to the re-specification of dI2 and dI3 neurons into dI4 interneurons. However, the role of Olig3 in regulating the development of ventral spinal cord has...
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