Article
The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord.
Genes & development - 15 Mar 2005
Müller Thomas, Anlag Katrin, Wildner Hendrik, Britsch Stefan, Treier Mathias, Birchmeier Carmen
Abstract excerpt
Neurons of the dorsal horn integrate and relay sensory information and arise during development in the dorsal spinal cord, the alar plate. Class A and B neurons emerge in the dorsal and ventral alar plate, differ in their dependence on roof plate signals for specification, and settle in the deep and superficial dorsal horn, respectively. We show here that the basic helix-loop-helix (bHLH) gene Olig3 is expressed...
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