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Article

Sim1 is required for the migration and axonal projections of V3 interneurons in the developing mouse spinal cord.

Developmental neurobiology - 1 Sept 2015

Blacklaws Jake, Deska-Gauthier Dylan, Jones Christopher T, Petracca Yanina L, Liu Mingwei, Zhang Han, Fawcett James P, Glover Joel C, Lanuza Guillermo M, Zhang Ying

Abstract excerpt

V3 spinal interneurons (INs) are a group of excitatory INs that play a crucial role in producing balanced and stable gaits in vertebrate animals. In the developing mouse spinal cord, V3 INs arise from the most ventral progenitor domain and form anatomically distinctive subpopulations in adult spinal cords. They are marked by the expression of transcription factor Sim1 postmitotically, but the function of Sim1 in...

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PMID: 25652362
DOI: 10.1002/dneu.22266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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