Article
Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.
Cell - 5 Apr 2002
Lu Q Richard, Sun Tao, Zhu Zhimin, Ma Nan, Garcia Meritxell, Stiles Charles D, Rowitch David H
Abstract excerpt
The oligodendrocyte lineage genes Olig1 and Olig2 encode related bHLH proteins that are coexpressed in neural progenitors. Targeted disruption of these two genes sheds light on the ontogeny of oligodendroglia and genetic requirements for their development from multipotent CNS progenitors. Olig2 i...
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