Article

Independent control of neurogenesis and dorsoventral patterning by NKX2-2

2024-10-13

Abstract excerpt

<h4>SUMMARY</h4> Human neurogenesis is disproportionately protracted, lasting >10 times longer than in mouse, allowing neural progenitors to undergo more rounds of self-renewing cell divisions and generate larger neuronal populations. In the human spinal cord, expansion of the motor neuron lineage is achieved through a newly evolved progenitor domain called vpMN (ventral motor neuron progenitor) that uniquely ext...

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Literature Corpus work: a5b5ce37-f097-5de6-90d0-064c2937b708
DOI: 10.1101/2024.10.13.618113

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