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Article

miR‐99a directly targets the <scp>mTOR</scp> signalling pathway in breast cancer side population cells

27 Oct 2014

Abstract excerpt

OBJECTIVES: miR-99a has been reported to function as a tumour suppressor in breast cancer. However, its role in the regulation of breast cancer stem cell (CSC) phenotype has up to now remained unknown. MATERIALS AND METHODS: In this study, we isolated the side population (SP) cells by staining cultured MCF-7 and MDA-MB-231 cells with fluorescent DNA-binding dye Hoechst 33342, then by flow cytometric sorting....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25348507
DOI: 10.1111/cpr.12146

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