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Article

A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype.

Breast cancer research : BCR - 14 Nov 2013

Wolf Jonas, Dewi Dyah Laksmi, Fredebohm Johannes, Müller-Decker Karin, Flechtenmacher Christa, Hoheisel Jörg D, Boettcher Michael

Abstract excerpt

INTRODUCTION: Breast cancer stem cells are suspected to be responsible for tumour recurrence, metastasis formation as well as chemoresistance. Consequently, great efforts have been made to understand the molecular mechanisms underlying cancer stem cell maintenance. In order to study these rare cells in-vitro, they are typically enriched via mammosphere culture. Here we developed a mammosphere-based negative...

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Identifiers

PMID: 24229464
DOI: 10.1186/bcr3576
PMCID: PMC3978845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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