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Article

Human pancreatic adenocarcinoma contains a side population resistant to gemcitabine

15 Aug 2012

Abstract excerpt

BACKGROUND: Therapy resistance remains one of the major challenges to improve the prognosis of patients with pancreatic cancer. Chemoresistant cells, which potentially also display cancer stem cell (CSC) characteristics, can be isolated using the side population (SP) technique. Our aim was to search for a SP in human pancreatic ductal adenocarcinoma (PDAC) and to examine its chemoresistance and CSC(-like)...

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PMID: 22894607
DOI: 10.1186/1471-2407-12-354

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