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Article

MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway.

Oncotarget - 8 Dec 2015

Liu Tong, Hu Kebang, Zhao Zuowei, Chen Guanglei, Ou Xunyan, Zhang Hao, Zhang Xin, Wei Xiaofei, Wang Dan, Cui Meizi, Liu Caigang

Abstract excerpt

We investigated the miRNA profiles of breast cancer stem cells (CSCs) and non-CSC tumor cells by miRNA microarray and determined the effect of altered miR-1 expression on proliferation and migration of breast CSCs. The potential targets of miR-1 in the Wnt/β-catenin signaling were characterized by bioinformatics analysis and luciferase assay. We found that 14 miRNAs were up-regulated and 13 were down-regulated in...

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Identifiers

PMID: 26497855
DOI: 10.18632/oncotarget.5873
PMCID: PMC4747178

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TNKS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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