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Article

Side population cells of pancreatic cancer show characteristics of cancer stem cells responsible for resistance and metastasis.

Targeted oncology - 1 Jun 2015

Niess Hanno, Camaj Peter, Renner Andrea, Ischenko Ivan, Zhao Yue, Krebs Stefan, Mysliwietz Josef, Jäckel Carsten, Nelson Peter J, Blum Helmut, Jauch Karl-Walter, Ellwart Joachim W, Bruns Christiane J

Abstract excerpt

Cancer stem cells (CSCs) have been proposed to underlie the initiation and maintenance of tumor growth and the development of chemoresistance in solid tumors. The identification and role of these important cells in pancreatic cancer remains controversial. Here, we isolate side population (SP) cells from the highly aggressive and metastatic human pancreatic cancer cell line L3.6pl and evaluate their potential role...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24950733
DOI: 10.1007/s11523-014-0323-z

Genes

ABCG2
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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