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Article

miR-125b regulates side population in breast cancer and confers a chemoresistant phenotype

20 Apr 2013

Abstract excerpt

Resistance to chemotherapy is a major obstacle for the effective treatment of breast cancer and is partially due to the presence of drug resistant stem cell-like side population (SP). Previous studies have shown elevated miR-125b is associated with chemoresistance and metastasis; however, the relationship between miR-125b and SP cells remains unknown. In this study, we isolated and characterized SP cells in a...

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PMID: 23606360
DOI: 10.1002/jcb.24574

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