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Article

Detection of putative cancer stem cells of the side population phenotype in human tumor cell cultures.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Christgen Matthias, Ballmaier Matthias, Lehmann Ulrich, Kreipe Hans

Abstract excerpt

Human solid tumors and clonal tumor cell lines comprise phenotypically and functionally diverse subsets of cancer cells and also contain stem cell-like cancer cells. Side population (SP) cells, which pump out the fluorescent dye Hoechst 33342 (H33342) via the ABCG2 transporter, define a fraction of adult tissue stem cells in a wide variety of organs. Rare cancer cells with similar H33342 efflux capacity and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22674135
DOI: 10.1007/978-1-61779-854-2_13

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Detection of putative cancer stem cells of the side population phenotype in human tumor cell cultures.PMID 22674135Read ↗

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Side Population: Its Use in the Study of Cellular Heterogeneity and as a Potential Enrichment Tool for Rare Cell PopulationsSemantic proximity Read ↗

Using ABCG2-molecule-expressing side population cells to identify cancer stem-like cells in a human ovarian cell lineSemantic proximity Read ↗

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