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Article

Identification of genetic drivers of plasma lipoprotein size in the Diversity Outbred mouse population.

Journal of lipid research - 1 Dec 2023

Price Tara R, Emfinger Christopher H, Schueler Kathryn L, King Sarah, Nicholson Rebekah, Beck Tim, Yandell Brian S, Summers Scott A, Holland William L, Krauss Ronald M, Keller Mark P, Attie Alan D

Abstract excerpt

Despite great progress in understanding lipoprotein physiology, there is still much to be learned about the genetic drivers of lipoprotein abundance, composition, and function. We used ion mobility spectrometry to survey 16 plasma lipoprotein subfractions in 500 Diversity Outbred mice maintained on a Western-style diet. We identified 21 quantitative trait loci (QTL) affecting lipoprotein abundance. To refine the...

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Identifiers

PMID: 37944753
DOI: 10.1016/j.jlr.2023.100471
PMCID: PMC10750189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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