Article

Identification of genetic drivers of plasma lipoproteins in the Diversity Outbred mouse population

2023-08-27

Abstract excerpt

Despite great progress in understanding lipoprotein physiology, there is still much to be learned about the genetic drivers of lipoprotein abundance, composition, and function. We used ion mobility spectrometry to survey 16 plasma lipoprotein subfractions in 500 Diversity Outbred (DO) mice maintained on a Western-style diet. We identified 21 quantitative trait loci (QTL) affecting lipoprotein abundance. To refine...

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Literature Corpus work: fa4ddf13-01ca-54b9-a81b-875dc98297c4
DOI: 10.1101/2023.08.26.554969

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