Article
CYP1A1 Ile462Val polymorphism and the risk of non-small cell lung cancer in a Chinese population.
Tumori - 1 Jan 2000
Lin Jia, He Bing, Cao Lei, Zhang Zhi, Liu Hongmei, Rao Juan, Liu Yingwen, Shao Shasha, Wang Guangxia, Zhang Xuemei
Abstract excerpt
AIMS AND BACKGROUND: Cytochrome P450 (CYP) 1A1 enzyme plays an important role in the metabolism of carcinogens, such as polycyclic aromatic hydrocarbons, nitroaromatics and arylamines. METHODS: The study examined the association of CYP1A1 Ile462Val polymorphism with the risk of developing non-small cell lung cancer in a Chinese population. We conducted a case-control study including 526 non-small cell lung cancer...
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