Article
CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women.
Lung cancer (Amsterdam, Netherlands) - 1 Apr 2008
Yoon Kyong-Ah, Kim Jin Hee, Gil Hyea-Jin, Hwang Hyukkee, Hwangbo Bin, Lee Jin Soo
Abstract excerpt
Polymorphisms in metabolic genes encoding phase I and phase II enzymes are thought to modulate the risk of lung cancer via changes in enzymatic activity. Recently, the effect of these metabolic enzymes and their interaction with environmental factors has been studied in both smokers and also never-smokers, since never-smokers are a good model in which to study genetic susceptibility at low-dose carcinogen...
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