Article
Investigation on XRCC1 genetic polymorphism and its relationship with breast cancer risk factors in Chinese women.
Medical oncology (Northwood, London, England) - 1 Dec 2013
Zheng Luming, Yang Feng, Zhang Xukui, Zhu Jian, Zhou Pen, Yu Fang, Hou Lei, Zhao Guowei, He Qingqing, Wang Baocheng
Abstract excerpt
Breast cancer (BC) remains one of the most common cancers among women. The human X-ray repair cross-complementing 1 (XRCC1) gene plays key roles in base excision repair, and genetic polymorphisms of XRCC1 may be associated with the susceptibility to BC. This study aimed to evaluate the relationship between the XRCC1 genetic polymorphisms and BC susceptibility. A total of 354 BC patients and 366 cancer-free...
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