Article
Impact of DNA repair genes polymorphism (XPD and XRCC1) on the risk of breast cancer in Egyptian female patients.
Molecular biology reports - 1 Feb 2012
Hussien Yousry Mostafa, Gharib Amal F, Awad Hanan A, Karam Rehab A, Elsawy Wael H
Abstract excerpt
The genes involved in DNA repair system play a crucial role in the protection against mutations. It has been hypothesized that functional deficiencies in highly conserved DNA repair processes resulting from polymorphic variation may increase genetic susceptibility to breast cancer (BC). The aim of the present study was to evaluate the association of genetic polymorphisms in 2 DNA repair genes, XPD (Asp312Asn) and...
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