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Article

XRCC1 Arg399Gln polymorphism confers risk of breast cancer in American population: a meta-analysis of 10846 cases and 11723 controls.

PloS one - 1 Jan 2014

Bu Tao, Liu Li, Sun Yong, Zhao Li, Peng Yang, Zhou Shudong, Li Lixia, Chen Sidong, Gao Yanhui

Abstract excerpt

BACKGROUND: In the X-ray repair cross-complementing group 1 (XRCC1) gene, a polymorphism, Arg399Gln (rs25487), has been shown to change neoconservative amino acid and thus result in alternation of DNA repair capacity. Numerous studies have investigated the association between Arg399Gln and breast cancer risk in the American population, but yielding inconsistent results. This study aimed to clarify the role of...

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Source

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Identifiers

PMID: 24489692
DOI: 10.1371/journal.pone.0086086
PMCID: PMC3904848

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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XRCC1 Arg399Gln polymorphism confers risk of breast cancer in American population: a meta-analysis of 10846 cases and 11723 controls.PMID 24489692Read ↗

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XRCC1 Arg399Gln gene polymorphism and breast cancer risk: a meta-analysis based on case-control studies.Semantic proximity Read ↗

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