Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide

29 Oct 2014

Abstract excerpt

// Kit Man Chai 1 , Chih-Yen Wang 1 , Hung-Jiun Liaw 1 , Kuan-Min Fang 1 , Chung-Shi Yang 2 , Shun-Fen Tzeng 1 1 Department of Life Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan City, 70101, Taiwan 2 Center for Nanomedicine Research, National Health Research Institutes, Zhunan, 35053, Taiwan correspondence to: Shun-Fen Tzeng, e-mail: stzeng@mail.ncku.edu.tw Key words:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to DNA Repair Mechanisms
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25337721
DOI: 10.18632/oncotarget.2543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomidePMID 25337721Read ↗

Induction Of XLF And 53BP1 Expression Is Associated With Temozolomide Resistance In Glioblastoma CellsSemantic proximity Read ↗

DNA repair mechanisms and their clinical impact in glioblastomaSemantic proximity Read ↗

FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZSemantic proximity Read ↗

DNA Damage Response and Repair: Insights Into Strategies for Radiation Sensitization of GliomasSemantic proximity Read ↗

Brahma-Related Gene-1 (BRG1) promotes the malignant phenotype of glioblastoma cells.Semantic proximity Read ↗

DNA Damage Response and Growth Factor Signaling Pathways in Gliomagenesis and Therapeutic ResistanceSemantic proximity Read ↗

BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicitySemantic proximity Read ↗

Role of BRCA1 in glioblastoma etiology.Semantic proximity Read ↗

Downregulated the expression of DNMT3B by suppressing PI3K/Akt signaling pathway and enhances the chemosensitivity of glioblastoma to temozolomide.Semantic proximity Read ↗

Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agentsSemantic proximity Read ↗

Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic GlioblastomaSemantic proximity Read ↗

RBBP4 regulates the expression of the Mre11-Rad50-NBS1 (MRN) complex and promotes DNA double-strand break repair to mediate glioblastoma chemoradiotherapy resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.