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Article

Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2016

Zannas Anthony S, Wiechmann Tobias, Gassen Nils C, Binder Elisabeth B

Abstract excerpt

Stress responses and related outcomes vary markedly across individuals. Elucidating the molecular underpinnings of this variability is of great relevance for developing individualized prevention strategies and treatments for stress-related disorders. An important modulator of stress responses is the FK506-binding protein 51 (FKBP5/FKBP51). FKBP5 acts as a co-chaperone that modulates not only glucocorticoid...

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Source

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Identifiers

PMID: 26250598
DOI: 10.1038/npp.2015.235
PMCID: PMC4677131

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications.PMID 26250598Read ↗

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The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders.Semantic proximity Read ↗

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