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Article

FKBP5 polymorphisms influence pre-learning stress-induced alterations of learning and memory.

The European journal of neuroscience - 1 Mar 2017

Zoladz Phillip R, Dailey Alison M, Nagle Hannah E, Fiely Miranda K, Mosley Brianne E, Brown Callie M, Duffy Tessa J, Scharf Amanda R, Earley McKenna B, Rorabaugh Boyd R

Abstract excerpt

FK506 binding protein 51 (FKBP5) is a co-chaperone of heat shock protein 90 and significantly influences glucocorticoid receptor sensitivity. Single nucleotide polymorphisms (SNPs) in the FKBP5 gene are associated with altered hypothalamus-pituitary-adrenal (HPA) axis function, changes in the structure and function of several cognitive brain areas, and increased susceptibility to post-traumatic stress disorder,...

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Share to FKBP5 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Stress, Psychological

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Source

Open in PubMed Open full text

Identifiers

PMID: 28002634
DOI: 10.1111/ejn.13514
PMCID: PMC5339029

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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