Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Risk Polymorphisms of FNDC5, BDNF, and NTRK2 and Poor Education Interact and Aggravate Age-Related Cognitive Decline.

International journal of molecular sciences - 7 Dec 2023

Tomás Alessandra Mendonça, Bento-Torres Natáli Valim Oliver, Jardim Naina Yuki Vieira, Moraes Patrícia Martins, da Costa Victor Oliveira, Modesto Antônio Conde, Khayat André Salim, Bento-Torres João, Picanço-Diniz Cristovam Wanderley

Abstract excerpt

Cognitive abilities tend to decline with aging, with variation between individuals, and many studies seek to identify genetic biomarkers that more accurately anticipate risks related to pathological aging. We investigated the influence of BDNF, NTRK2, and FNDC5 single nucleotide polymorphisms (SNPs) on the cognitive performance of young and older adults with contrasting educational backgrounds. We addressed three...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Cognition

Share to Cognitive Dysfunction

Share to Fibronectins

Share to Memory, Episodic

Share to Neuropsychological Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 38139046
DOI: 10.3390/ijms242417210
PMCID: PMC10743741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk Polymorphisms of FNDC5, BDNF, and NTRK2 and Poor Education Interact and Aggravate Age-Related Cognitive Decline.PMID 38139046Read ↗

Genetic effects on old-age cognitive functioning: a population-based study.Semantic proximity Read ↗

BDNF variants, premorbid educational attainment, and disease characteristics in Alzheimer's disease: an exploratory study.Semantic proximity Read ↗

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.Semantic proximity Read ↗

Education as a Modifier of Genetic Influence on Cognitive Ability in Older Adults.Semantic proximity Read ↗

The genetics of cognitive ability and cognitive ageing in healthy older people.Semantic proximity Read ↗

Association of genetic risk factors with cognitive decline: the PATH through life project.Semantic proximity Read ↗

Cognitive performance protects against Alzheimer's disease independently of educational attainment and intelligence.Semantic proximity Read ↗

NRSF and BDNF polymorphisms as biomarkers of cognitive dysfunction in adults with newly diagnosed epilepsy.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) gene: a gender-specific role in cognitive function during normal cognitive aging of the MEMO-Study?Semantic proximity Read ↗

Genetics and functional imaging: effects of APOE, BDNF, COMT, and KIBRA in aging.Semantic proximity Read ↗

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment.Semantic proximity Read ↗

Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.