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Article

Inactivation of PTCH1 is associated with the development of cervical carcinoma: clinical and prognostic implication.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2015

Chakraborty Chandraditya, Dutta Sankhadeep, Mukherjee Nupur, Samadder Sudip, Roychowdhury Anirban, Roy Anup, Mondal Ranajit Kumar, Basu Partha, Roychoudhury Susanta, Panda Chinmay Kumar

Abstract excerpt

The aim of this study was to analyze the alterations of PTCH1 (deletion/promoter methylation/mutation/expression) during the development of cervical cancer (CACX). For this purpose, deletion/methylation of PTCH1 were analyzed in HPV16 positive exfoliated asymptomatic cervical swabs (n = 74), cervical intraepithelial neoplasia (CIN) (n = 32), CACX (n = 174) samples, and two CACX cell lines. The deletion of PTCH1...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25330948
DOI: 10.1007/s13277-014-2707-1

Genes

PTCH1
GLI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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