Article
[Effects of PTCH1 mutations on the epithelial proliferation derived from keratocystic odontogenic tumour].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Jun 2017
Abstract excerpt
OBJECTIVE: To explore the relationship between the PTCH1 mutation and the expression of bcl-2, filaggrin, and loricrin in the keratocystic odontogenic tumour (KCOT), as well as the effects of the mutated PTCH1 on the epithelial proliferation and differentiation. METHODS: The samples were collected from 20 cases of KCOT with mutated PTCH1, as well as 20 cases without mutation. All the samples were analyzed with...
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