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Article

The vesicle protein SAM-4 regulates the processivity of synaptic vesicle transport.

PLoS genetics - 1 Oct 2014

Zheng Qun, Ahlawat Shikha, Schaefer Anneliese, Mahoney Tim, Koushika Sandhya P, Nonet Michael L

Abstract excerpt

Axonal transport of synaptic vesicles (SVs) is a KIF1A/UNC-104 mediated process critical for synapse development and maintenance yet little is known of how SV transport is regulated. Using C. elegans as an in vivo model, we identified SAM-4 as a novel conserved vesicular component regulating SV t...

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Identifiers

PMID: 25329901
DOI: 10.1371/journal.pgen.1004644
PMCID: PMC4199485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-25329901-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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