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Vps54 regulates <i>Drosophila</i> neuromuscular junction development and controls postsynaptic density composition via a Rab7-dependent mechanism

2020-02-17

Abstract excerpt

<h4>ABSTRACT</h4> Vps54 is a subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans -Golgi network (TGN). In the wobbler mouse, a model for human motor neuron (MN) disease, reduction in the levels of Vps54 causes neurodegeneration. However, it is unclear how disruption of GARP-mediated vesicle transport leads to MN dysfunction and...

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Literature Corpus work
28cd29bb-5634-5296-a6f3-47e61808c73e
DOI
10.1101/2020.02.17.952721
Open publication

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