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Article

UNC-41/stonin functions with AP2 to recycle synaptic vesicles in Caenorhabditis elegans.

PloS one - 1 Jan 2012

Mullen Gregory P, Grundahl Kiely M, Gu Mingyu, Watanabe Shigeki, Hobson Robert J, Crowell John A, McManus John R, Mathews Eleanor A, Jorgensen Erik M, Rand James B

Abstract excerpt

The recycling of synaptic vesicles requires the recovery of vesicle proteins and membrane. Members of the stonin protein family (Drosophila Stoned B, mammalian stonin 2) have been shown to link the synaptic vesicle protein synaptotagmin to the endocytic machinery. Here we characterize the unc-41 gene, which encodes the stonin ortholog in the nematode Caenorhabditis elegans. Transgenic expression of Drosophila...

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Identifiers

PMID: 22808098
DOI: 10.1371/journal.pone.0040095
PMCID: PMC3393740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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UNC-41/stonin functions with AP2 to recycle synaptic vesicles in Caenorhabditis elegans.PMID 22808098Read ↗

Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2.Semantic proximity Read ↗

UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles.Semantic proximity Read ↗

Drosophila stoned proteins regulate the rate and fidelity of synaptic vesicle internalization.Semantic proximity Read ↗

Mutations in synaptojanin disrupt synaptic vesicle recycling.Semantic proximity Read ↗

Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans.Semantic proximity Read ↗

Interaction of stoned and synaptotagmin in synaptic vesicle endocytosis.Semantic proximity Read ↗

Endophilin is required for synaptic vesicle endocytosis by localizing synaptojanin.Semantic proximity Read ↗

The products of the Drosophila stoned locus interact with synaptic vesicles via synaptotagmin.Semantic proximity Read ↗

UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants.Semantic proximity Read ↗

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The JIP3 scaffold protein UNC-16 regulates RAB-5 dependent membrane trafficking at C. elegans synapses.Semantic proximity Read ↗

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