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Article

Break-induced replication requires DNA damage-induced phosphorylation of Pif1 and leads to telomere lengthening.

PLoS genetics - 1 Oct 2014

Vasianovich Yulia, Harrington Lea A, Makovets Svetlana

Abstract excerpt

Broken replication forks result in DNA breaks that are normally repaired via homologous recombination or break induced replication (BIR). Mild insufficiency in the replicative ligase Cdc9 in budding yeast Saccharomyces cerevisiae resulted in a population of cells with persistent DNA damage, most...

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Identifiers

PMID: 25329304
DOI: 10.1371/journal.pgen.1004679
PMCID: PMC4199488

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25329304-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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