Article
Hormone-related pathways and risk of breast cancer subtypes in African American women.
Breast cancer research and treatment - 1 Nov 2015
Haddad Stephen A, Lunetta Kathryn L, Ruiz-Narváez Edward A, Bensen Jeannette T, Hong Chi-Chen, Sucheston-Campbell Lara E, Yao Song, Bandera Elisa V, Rosenberg Lynn, Haiman Christopher A, Troester Melissa A, Ambrosone Christine B, Palmer Julie R
Abstract excerpt
We sought to investigate genetic variation in hormone pathways in relation to risk of overall and subtype-specific breast cancer in women of African ancestry (AA). Genotyping and imputation yielded data on 143,934 SNPs in 308 hormone-related genes for 3663 breast cancer cases (1098 ER-, 1983 ER+, 582 ER unknown) and 4687 controls from the African American Breast Cancer Epidemiology and Risk (AMBER) Consortium....
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