Article
Loss of heterozygosity of chromosome 13q33-34 region and molecular analysis of ING1 and p53 genes in bladder carcinoma.
Molecular biology reports - 1 Feb 2015
Igci Mehri, Arslan Ahmet, Erturhan Sakip, Igci Yusuf Ziya, Pala Elif, Gogebakan Bulent, Karakok Metin, Cakmak Ecir Ali, Cengiz Beyhan
Abstract excerpt
Cancer is a consequence of accumulation of genetic and epigenetic alterations in the cell which can lead to activation of oncogenes or inactivation of tumor suppressor genes (TSG). Since members of ING family were discovered as TSGs in different cancer types, it was aimed to analyze the chromosom...
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