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Article

Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers.

Oncogene - 27 Jun 2002

Gunduz Mehmet, Ouchida Mamoru, Fukushima Kunihiro, Ito Sachio, Jitsumori Yoshimi, Nakashima Tomoko, Nagai Noriyuki, Nishizaki Kazunori, Shimizu Kenji

Abstract excerpt

Loss of heterozygosity (LOH) has been frequently detected at chromosome 7q31 region in human head and neck squamous cell carcinomas (HNSCC) and many other cancers, suggesting the existence of tumor suppressor genes (TSG). We analysed LOH at 7q31 region in 49 HNSCC by using six polymorphic microsatellite markers and found allelic deletion in 48% (22/46) of the informative cases. We detected two preferentially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12080476
DOI: 10.1038/sj.onc.1205540

Genes

ING3
ING1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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