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Article

The candidate tumour suppressor gene, ING1, is retained in colorectal carcinomas.

European journal of cancer (Oxford, England : 1990) - 1 Aug 1999

Sarela A I, Farmery S M, Markham A F, Guillou P J

Abstract excerpt

ING1 plays a critical role in regulating cell cycle progression and susceptibility to apoptosis. The present study aimed to investigate allelic deletion of, and mutations within, the ING1 gene in colorectal carcinomas. Genomic DNA was extracted from 29 sporadic colorectal carcinomas and samples of adjacent normal mucosa. Losses of heterozygosity of two polymorphic dinucleotide repeat markers close to the ING1...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10615239
DOI: 10.1016/s0959-8049(99)00104-5

Genes

ING1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The candidate tumour suppressor gene, ING1, is retained in colorectal carcinomas.PMID 10615239Read ↗

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