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Article

Hypermethylation of an E-cadherin (CDH1) promoter region in high grade transitional cell carcinoma of the bladder comprising carcinoma in situ.

The Journal of urology - 1 Apr 2003

Horikawa Yohei, Sugano Kokichi, Shigyo Masanori, Yamamoto Hidenobu, Nakazono Masaaki, Fujimoto Hiroyuki, Kanai Yae, Hirohashi Setsuo, Kakizoe Tadao, Habuchi Tomonori, Kato Tetsuro

Abstract excerpt

PURPOSE: We elucidated the role of methylation in the promoter region of the 1 gene in bladder carcinogenesis, particularly in those comprising carcinoma in situ. MATERIALS AND METHODS: A total of 49 cases of transitional cell carcinoma of the bladder obtained from transurethral resection were examined. Methylation status of the 1 promoter region was analyzed by methylation specific polymerase chain reaction from...

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Source

Identifiers

PMID: 12629411
DOI: 10.1097/01.ju.0000046242.55722.1c

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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