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Article

Integrative modeling of multi-platform genomic data under the framework of mediation analysis.

Statistics in medicine - 15 Jan 2015

Huang Yen-Tsung

Abstract excerpt

Given the availability of genomic data, there have been emerging interests in integrating multi-platform data. Here, we propose to model genetics (single nucleotide polymorphism (SNP)), epigenetics (DNA methylation), and gene expression data as a biological process to delineate phenotypic traits under the framework of causal mediation modeling. We propose a regression model for the joint effect of SNPs,...

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Identifiers

PMID: 25316269
DOI: 10.1002/sim.6326
PMCID: PMC4262570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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