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Article

Dissecting the colocalized GWAS and eQTLs with mediation analysis for high-dimensional exposures and confounders.

Biometrics - 27 Mar 2024

Zhang Qi, Yang Zhikai, Yang Jinliang

Abstract excerpt

To leverage the advancements in genome-wide association studies (GWAS) and quantitative trait loci (QTL) mapping for traits and molecular phenotypes to gain mechanistic understanding of the genetic regulation, biological researchers often investigate the expression QTLs (eQTLs) that colocalize with QTL or GWAS peaks. Our research is inspired by 2 such studies. One aims to identify the causal single nucleotide...

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PMID: 38801257
DOI: 10.1093/biomtc/ujae050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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