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Article

Integrative modeling of multiple genomic data from different types of genetic association studies.

Biostatistics (Oxford, England) - 1 Oct 2014

Huang Yen-Tsung

Abstract excerpt

Genome-wide association studies (GWASs) and expression-/methylation-quantitative trait loci (eQTL/mQTL) studies constitute popular approaches for investigating the association of single nucleotide polymorphisms (SNPs) with disease and expression/methylation, respectively. Here, we propose to integrate QTL studies to more powerfully test the SNP effect on disease in GWASs when they are conducted among different...

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PMID: 24705142
DOI: 10.1093/biostatistics/kxu014

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