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Article

Intraclonal diversity in follicular lymphoma analyzed by quantitative ultradeep sequencing of noncoding regions.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2014

Spence Janice M, Abumoussa Andrew, Spence John P, Burack W Richard

Abstract excerpt

Cancers are characterized by genomic instability, and the resulting intraclonal diversity is a prerequisite for tumor evolution. Therefore, metrics of tumor heterogeneity may prove to be clinically meaningful. Intraclonal heterogeneity in follicular lymphoma (FL) is apparent from studies of somat...

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Share to AICDA (Activation-Induced Cytidine Deaminase)
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Identifiers

PMID: 25311808
DOI: 10.4049/jimmunol.1401699
PMCID: PMC4225181

Genes

IGH
BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25311808-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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