Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal Complexity Defines Distinct Tumor-Intrinsic Biology and Prognosis in Diffuse Large B-Cell Lymphoma.

Cancer medicine - 1 Feb 2026

Haeno Takahiro, Sakai Kazuko, Minamoto Shuji, Nakatsu Daiki, De Velasco Marco A, Rai Shinya, Tanaka Hirokazu, Matsumura Itaru, Nishio Kazuto

Abstract excerpt

BACKGROUND: Intratumor heterogeneity (ITH), characterized by the coexistence of genetically distinct subclones within a tumor, has been associated with adverse clinical outcomes in various cancers. However, the clinical and biological implications of ITH in diffuse large B-cell lymphoma (DLBCL) are still incompletely understood. MATERIALS & METHODS: In this study, we applied a SNP-array-based approach to assess...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to STAT3 gene

Share to Lymphoma, Large B-Cell, Diffuse

Share to Mutation

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 41629261
DOI: 10.1002/cam4.71597
PMCID: PMC12863995

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal Complexity Defines Distinct Tumor-Intrinsic Biology and Prognosis in Diffuse Large B-Cell Lymphoma.PMID 41629261Read ↗

Biological heterogeneity in diffuse large B-cell lymphomaSemantic proximity Read ↗

Mutational Intratumor Heterogeneity is a Complex and Early Event in the Development of Adult T-cell Leukemia/Lymphoma.Semantic proximity Read ↗

Decoding the Heterogeneity of Diffuse Large B-Cell Lymphomas: A Comprehensive Genetic, Transcriptomic, and Phenotypic Profiling of B-Cell Lymphoma Cell Lines.Semantic proximity Read ↗

Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.Semantic proximity Read ↗

Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma.Semantic proximity Read ↗

Cell-of-Origin Subtyping of Diffuse Large B-Cell Lymphoma by Using a qPCR-based Gene Expression Assay on Formalin-Fixed Paraffin-Embedded TissuesSemantic proximity Read ↗

A single-cell atlas of diffuse large B cell lymphomaSemantic proximity Read ↗

Single-Cell RNA-Seq and Bulk RNA-Seq Reveal Intratumoral Heterogeneity and Tumor Microenvironment Characteristics in Diffuse Large B-Cell LymphomaSemantic proximity Read ↗

Are We Ready To Stratify Treatment for Diffuse Large B-Cell Lymphoma Using Molecular Hallmarks?Semantic proximity Read ↗

Genetic subtyping by Whole Exome Sequencing across Diffuse Large B Cell Lymphoma and Plasmablastic LymphomaSemantic proximity Read ↗

High-grade B-cell lymphoma, not otherwise specified: an LLMPP studySemantic proximity Read ↗

Deconvolution of B-cell heterogeneity identifies PDIA6 as a prognostic driver in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.