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Article

Association of ARRB1 polymorphisms with the risk of major depressive disorder and with treatment response to mirtazapine.

Journal of psychopharmacology (Oxford, England) - 1 May 2015

Chang Hun Soo, Won Eun Soo, Lee Hwa-Young, Ham Byung-Joo, Kim Yong-Gu, Lee Min-Soo

Abstract excerpt

β-Arrestin 1 is known to be involved in the pathophysiology of major depressive disorder (MDD) and in the underlying mechanism of action of antidepressant therapies. After we screened 39 ARRB1 polymorphisms, we investigated the associations of seven ARRB1 single-nucleotide polymorphisms (SNPs) with the risk of MDD in 270 patients with MDD and 204 normal subjects, and with mirtazapine treatment response in...

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Source

Identifiers

PMID: 25294870
DOI: 10.1177/0269881114554273

Genes

ARRB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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