Article
The association of β-arrestin2 polymorphisms with response to antidepressant treatment in depressed patients.
Progress in neuro-psychopharmacology & biological psychiatry - 2 Feb 2018
Petit Anne-Cécile, El Asmar Khalil, David Denis J, Gardier Alain M, Becquemont Laurent, Fève Bruno, Verstuyft Céline, Corruble Emmanuelle
Abstract excerpt
The study of genetic polymorphisms involved in antidepressants (AD) response is essential to provide a personalized medicine approach in the field of depression. β-arrestin 2 (ARRB2) is a candidate gene in the pharmacogenetics of AD as it is involved in the signaling cascade downstream of numerous neurotransmitter receptors. We investigated the association between five ARRB2 single nucleotide polymorphisms...
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