Article
HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort.
Neuromolecular medicine - 1 Sept 2010
Kishi Taro, Yoshimura Reiji, Kitajima Tsuyoshi, Okochi Tomo, Okumura Takenori, Tsunoka Tomoko, Yamanouchi Yoshio, Kinoshita Yoko, Kawashima Kunihiro, Naitoh Hiroshi, Nakamura Jun, Ozaki Norio, Iwata Nakao
Abstract excerpt
Several recent investigations reported that the serotonin 2A receptor gene (HTR2A) was associated with selective serotonin reuptake inhibitors (SSRIs) in major depressive disorder. There have also been two reported association analyses of HTR2A with SSRI response in Japanese MDD patients, but the results were rather inconsistent and both studies had the problem of small sample sizes. Therefore, we conducted a...
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