Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans.

Molecular psychiatry - 1 Dec 2009

Dong C, Wong M-L, Licinio J

Abstract excerpt

We studied seven genes that reflect events relevant to antidepressant action at four sequential levels: (1) entry into the brain, (2) binding to monoaminergic transporters, and (3) distal effects at the transcription level, resulting in (4) changes in neurotrophin and neuropeptide receptors. Those genes are ATP-binding cassette subfamily B member 1 (ABCB1), the noradrenaline, dopamine, and serotonin transporters...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents
Share to ATP Binding Cassette Transporter 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CRF Receptor, Type 1

Share to Cyclic AMP Response Element-Binding Protein

Share to Mexican Americans

Share to Norepinephrine Plasma Membrane Transport Proteins

Share to Receptor, trkB

Share to Receptors, Corticotropin-Releasing Hormone

Source

Open in PubMed Open full text

Identifiers

PMID: 19844206
DOI: 10.1038/mp.2009.92
PMCID: PMC2834349

Genes

NTRK2
ABCB1
CRHR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans.PMID 19844206Read ↗

Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response.Semantic proximity Read ↗

Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication.Semantic proximity Read ↗

ABCB1 Gene Variants and Antidepressant Treatment Outcomes: A Systematic Review and Meta-Analysis Including Results from the CAN-BIND-1 Study.Semantic proximity Read ↗

Exon sequencing and high resolution haplotype analysis of ABC transporter genes implicated in drug resistance.Semantic proximity Read ↗

Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway.Semantic proximity Read ↗

Case-control association study of 36 single-nucleotide polymorphisms within 10 candidate genes for major depression and bipolar disorder.Semantic proximity Read ↗

Association between the functional polymorphism (C3435T) of the gene encoding P-glycoprotein (ABCB1) and major depressive disorder in the Japanese population.Semantic proximity Read ↗

Association of ARRB1 polymorphisms with the risk of major depressive disorder and with treatment response to mirtazapine.Semantic proximity Read ↗

Sequence polymorphisms of MC1R gene and their association with depression and antidepressant response.Semantic proximity Read ↗

Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein.Semantic proximity Read ↗

A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressantsSemantic proximity Read ↗

Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.